Tapentadol 100mg (Aspadol 100mg, Typendol 100mg)
$150.00 – $400.00
| Manufacturer : | Signature Pharma |
| Country Of Origin : | India |
| Dosage Form : | Tablet |
| Indication : | Pain Relief |
| Packaging : | 10 Tablet in Strip |
| Delivery Time: | 6 to 15 Days Delivery Time |
| Active Ingredient : | Tapentadol |
| US Brand Name: | Generic Nucynta |
Description
What is Tapentadol?
Tapentadol is a synthetic opioid analgesic that works by altering the way the brain and nervous system respond to pain. It is used to relieve moderate to severe pain and is available by prescription under various brand names, including Nucynta and Nucynta ER (extended-release).
Tapentadol is a prescription medication used primarily for the management of moderate to severe pain. It is classified as a narcotic analgesic and is known for its dual mechanism of action, combining opioid and non-opioid pain relief properties. Tapentadol is used in various clinical settings, including acute pain, chronic pain, and as part of postoperative pain management.
Mechanism of Action
Tapentadol has a dual mechanism of action:
- Opioid Receptor Agonism: Tapentadol binds to the mu-opioid receptors in the brain and spinal cord, which helps in alleviating pain by modifying pain perception and response.
- Norepinephrine Reuptake Inhibition: Tapentadol also inhibits the reuptake of norepinephrine, a neurotransmitter involved in pain modulation. This non-opioid mechanism contributes to its analgesic effect and helps in managing pain through a different pathway.
Dosage Forms and Strengths
Tapentadol is available in several forms, each designed to meet specific pain management needs:
- Immediate-Release Tablets: Typically available in strengths of 50 mg, 75 mg, and 100 mg. These tablets provide relief from acute pain and are usually taken every 4 to 6 hours as needed.
- Extended-Release Tablets: Available in strengths of 50 mg, 100 mg, 150 mg, 200 mg, and 250 mg. Extended-release tablets are designed for continuous pain management and are usually taken every 12 hours.
Dosage and Administration
- Immediate-Release Tablets: The usual starting dose is 50 mg every 4 to 6 hours as needed. The dose may be adjusted based on the severity of pain and patient response.
- Extended-Release Tablets: The starting dose is typically 50 mg every 12 hours. The dose can be adjusted based on the patient’s pain level, but it should not exceed the maximum recommended dose.
Administration: Tapentadol tablets should be swallowed whole and not crushed or chewed, especially the extended-release form, to avoid rapid release of the drug, which can increase the risk of side effects.
Duration of Action
- Immediate-Release Tablets: Provide pain relief for approximately 4 to 6 hours per dose.
- Extended-Release Tablets: Provide pain relief for up to 12 hours, allowing for twice-daily dosing.
Side Effects
Common side effects of tapentadol include:
- Gastrointestinal Issues: Nausea, vomiting, constipation.
- Central Nervous System Effects: Dizziness, drowsiness, headache.
- Respiratory Issues: Respiratory depression, which can be serious, especially with higher doses.
Serious side effects may include:
- Addiction, Abuse, and Misuse: Tapentadol can lead to physical and psychological dependence.
- Severe Respiratory Depression: Especially if misused or if used in combination with other central nervous system depressants.
- Hypotension: Low blood pressure, which can cause dizziness or fainting.
Precautions and Warnings
- Addiction and Dependence: Tapentadol has the potential for abuse and addiction. It should be used with caution in patients with a history of substance abuse or mental illness.
- Respiratory Depression: Monitor for respiratory depression, especially in opioid-naive patients or when used with other CNS depressants.
- Liver and Kidney Function: Use with caution in patients with liver or kidney impairment as these conditions can affect drug metabolism and clearance.
- Drug Interactions: Tapentadol can interact with other medications, including other CNS depressants, MAO inhibitors, and certain antidepressants. Inform your healthcare provider about all medications and supplements you are taking.
Contraindications
Tapentadol should not be used in:
- Individuals with severe respiratory depression or acute or severe asthma.
- Patients who are hypersensitive to tapentadol or any other component of the medication.
- Individuals with paralytic ileus (a type of bowel obstruction).
Storage
- Tablets: Store at room temperature, away from moisture and heat. Keep out of reach of children and secure to prevent misuse.
Important Considerations
- Compliance: Adhere to the prescribed dosing schedule and do not alter the dosage without consulting your healthcare provider.
- Disposal: Dispose of unused or expired tapentadol tablets properly to prevent misuse. Many pharmacies offer drug take-back programs.
- Monitoring: Regularly monitor for signs of misuse, addiction, or adverse effects and consult your healthcare provider for adjustments in treatment if needed.
Here are some very short FAQs about Tapentadol:
1. What is it used for?
Answer: It is used to manage moderate to severe pain.
2. How does it work?
Answer: It works by binding to opioid receptors and inhibiting norepinephrine reuptake to relieve pain.
3. What are the available forms of Tapentadol?
Answer: It is available in immediate-release and extended-release tablets.
4. What are the common side effects of it?
Answer: Common side effects include nausea, dizziness, and constipation.
5. How should Tapentadol be taken?
Answer: It should be swallowed whole, with or without food, as prescribed.
6. Can Tapentadol cause addiction?
Answer: Yes, it has the potential for addiction and should be used as directed.
7. What should I do if I miss a dose?
Answer: Take the missed dose as soon as you remember, but skip it if it’s almost time for the next dose. Do not double up.
8. Is it safe during pregnancy?
Answer: It is generally not recommended during pregnancy unless necessary. Consult a healthcare provider.
Other Meds:-
Summary
Tapentadol is an effective medication for managing moderate to severe pain through its unique dual mechanism of action, offering both opioid and non-opioid pain relief. It is available in immediate-release and extended-release formulations to accommodate different pain management needs. Proper use and adherence to prescribed guidelines are crucial to minimize risks and maximize the benefits of this medication. Always consult with a healthcare provider for personalized advice and adjustments to treatment.
Additional information
| mg | Aspadol 100mg, Typendol 100mg |
|---|---|
| unit | 100 Tablets, 200 Tablets, 300 Tablets |
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